Side Effects for Vyvanse
(lisdexamfetamine dimesylate)

It's important to understand the benefits and risks

It's important to understand the potential benefits and risks before starting treatment. Please keep in mind that this is not a complete list of risk information for Vyvanse. For additional safety information, please see Vyvanse Prescribing Information and Medication Guide and discuss them with your doctor.

What important information should I know about Vyvanse?


Vyvanse has a high risk of abuse or dependence. Keep in a safe place to prevent misuse and abuse. Selling or sharing Vyvanse may harm others and is illegal.

Tell your doctor if you or your child has ever abused or been dependent on alcohol, prescription medicines or street drugs.

Vyvanse is a stimulant medicine. Some people have had the following problems when taking stimulant medicines such as Vyvanse:

  1. 1. Heart-related problems including:
    • sudden death in people who have heart problems or heart defects
    • sudden death, stroke and heart attack in adults
    • increased blood pressure and heart rate

Tell your doctor if you or your child has any heart problems, heart defects, high blood pressure, or a family history of these problems.

Your doctor should check you or your child carefully for heart problems before starting Vyvanse.

Your doctor should check your or your child’s blood pressure and heart rate regularly during treatment with Vyvanse.
Call your doctor right away if you or your child has any signs of heart problems such as chest pain, shortness of breath, or fainting while taking Vyvanse.

  1. 2. Mental (psychiatric) problems including:

    In Children, Teenagers, and Adults:

    • new or worse behavior and thought problems
    • new or worse bipolar illness

    In Children and Teenagers

    • new psychotic symptoms such as:
      • hearing voices
      • believing things that are not true
      • being suspicious
    • new manic symptoms

Tell your doctor about any mental problems you or your child has, or about a family history of suicide, bipolar illness, or depression.
Call your doctor right away if you or your child has any new or worsening mental symptoms or problems while taking Vyvanse, especially:

  • seeing or hearing things that are not real
  • believing things that are not real
  • being suspicious

Who should not take Vyvanse?

Do not take Vyvanse if you:

  • Are taking or have taken within the last 14 days an anti-depression medicine called a monoamine oxidase inhibitor or MAOI
  • Are sensitive to allergic to, or had a reaction to other stimulant medicines

What are the most common side effects of Vyvanse?

The most common side effects of Vyvanse include anxiety, decreased appetite, diarrhea, dizziness, dry mouth, irritability, loss of appetite, nausea, trouble sleeping, upper stomach pain, vomiting, and weight loss.

These are not all the possible side effects of Vyvanse. Talk to your doctor about any side effects you may be experiencing.

What should I ask my doctor about Vyvanse?

See questions

For more information

Please see Vyvanse Prescribing Information and Medication Guide and discuss with your doctor or pharmacist.

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